SELENON

Across TCGA cell cohorts, SELENON RNA expression is significantly associated with the go_rna of many other GO terms, with 4,334 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SELENON-associated GO terms across cancer lineages are Positive regulation of response to oxidative stress, Skeletal muscle tissue regeneration, and Regulation of cell-substrate junction organization. Each is linked with SELENON in more than 15 cancer types. Because this analysis shows association rather than direction, both SELENON-to-partner and partner-to-SELENON results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of response to oxidative stress grouped by SELENON-low versus SELENON-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENON→partner) and Y-score (partner→SELENON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of response to oxidative stress →	+0.219	+1.110	<.001	<.001	3	16
LIVER	Skeletal muscle tissue regeneration →	+0.180	+0.942	.001	.003	3	12
BREAST	Regulation of cell-substrate junction organization →	+0.073	+0.531	<.001	.003	3	12
SKIN	Organelle transport along microtubule →	+0.065	+0.853	<.001	.003	3	12
SKIN	Protein localization to cytoskeleton →	+0.077	+0.815	<.001	.006	3	11
LUNG_NSCLC_LUSC	Regulation of focal adhesion assembly →	+0.080	+1.644	.003	.003	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,334 associations by consensus.

Positive regulation of response to oxidative stress by SELENON expression — SKIN

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