Across TCGA patient cohorts, SELENOM protein abundance is significantly associated with the RNA expression of many other genes, with 14,598 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SELENOM-associated genes across cancer lineages are DCN, SERPINF1, and LUM. Each is linked with SELENOM in more than 7 cancer types. Because this analysis shows association rather than direction, both SELENOM-to-partner and partner-to-SELENOM results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOM→partner) and Y-score (partner→SELENOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DCN →	+1.418	+0.575	<.001	<.001	3	8
OV	SERPINF1 →	+1.721	+0.532	<.001	<.001	3	8
GBM	LUM →	+1.938	+0.540	<.001	<.001	3	8
OV	C1R →	+1.012	+0.506	<.001	<.001	3	8
OV	C1S →	+1.282	+0.606	<.001	<.001	3	8
OV	CXCL12 →	+1.429	+0.584	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,598 associations by consensus.

Exploration

SELENOM survival (RNA) · tumor vs normal (RNA) · all SELENOM data types