Across TCGA patient cohorts, SELENOF protein abundance is significantly associated with the RNA expression of many other genes, with 13,721 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SELENOF-associated genes across cancer lineages are FAM131A, WNT3, and ANKRD40. Each is linked with SELENOF in more than 4 cancer types. Because this analysis shows association rather than direction, both SELENOF-to-partner and partner-to-SELENOF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOF→partner) and Y-score (partner→SELENOF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM131A →	-0.693	-0.253	<.001	<.001	3	5
BRCA	WNT3 →	-0.814	-0.245	<.001	<.001	3	5
LSCC	ANKRD40 →	-0.409	-0.206	<.001	<.001	3	5
COAD	CRYAB →	-1.136	-0.281	<.001	<.001	3	4
LSCC	CLCN2 →	-0.772	-0.299	<.001	<.001	3	4
UCEC	RUNX2 →	+1.382	+0.294	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,721 associations by consensus.

Exploration

SELENOF survival (RNA) · tumor vs normal (RNA) · all SELENOF data types