Across TCGA patient cohorts, SELENOF mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOF-associated genes across cancer lineages are MIR6515, ATP6V1E1P2, and SMC4P1. Each is linked with SELENOF in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENOF-to-partner and partner-to-SELENOF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOF→partner) and Y-score (partner→SELENOF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6515 →	+0.717	+8.055	<.001	.007	3	2
UCEC	ATP6V1E1P2 →	+0.193	+3.398	.002	.001	3	2
LUSC	SMC4P1 →	+0.135	+5.548	<.001	.004	3	2
BLCA	MIR4305 →	+0.433	+5.177	<.001	.007	3	1
BLCA	TBC1D3P4 →	+0.038	+6.444	<.001	.001	3	1
BRCA	RNU6-1103P →	+0.269	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

SELENOF survival (RNA) · tumor vs normal (RNA) · all SELENOF data types