SELENBP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SELENBP1 mutation is significantly associated with the RNA expression of many other genes, with 1,015 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENBP1-associated genes across cancer lineages are SURF6P1, RNU7-52P, and LSP1P3. Each is linked with SELENBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENBP1-to-partner and partner-to-SELENBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SURF6P1 grouped by SELENBP1-low versus SELENBP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENBP1→partner) and Y-score (partner→SELENBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADSURF6P1 →+0.279+5.868<.001<.00132
PRADRNU7-52P →+0.503+7.939<.001.00832
LIHCLSP1P3 →+0.257+5.066.001.00132
LIHCLINC00459 →+0.086+6.495<.001<.00132
LIHCRPL5P26 →+0.049+4.648.004.00432
UCECASB16-AS1 →+0.375+2.595.005.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,015 associations by consensus.

SURF6P1 by SELENBP1 expression — COAD

Box plot of SURF6P1 in SELENBP1-low vs SELENBP1-high samples in COAD.

Explore this box plot interactively →

Exploration