SEL1L3

Across TCGA patient cohorts, SEL1L3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,691 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SEL1L3-associated genes across cancer lineages are EFS, ECHDC3, and ARHGEF4. Each is linked with SEL1L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SEL1L3-to-partner and partner-to-SEL1L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEL1L3 versus EFS in GBM, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEL1L3→partner) and Y-score (partner→SEL1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EFS →	-0.872	-0.815	<.001	<.001	3	3
LUAD	ECHDC3 →	-0.998	-0.432	<.001	<.001	3	3
LSCC	ARHGEF4 →	-1.000	-0.310	<.001	<.001	3	3
GBM	CDHR1 →	-1.508	-0.969	<.001	<.001	3	3
PDAC	BACE2 →	+0.752	+0.402	<.001	<.001	3	3
BRCA	IL15 →	+0.876	+0.669	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,691 associations by consensus.

SEL1L3 vs EFS — GBM

Explore this scatter interactively →