SEL1L3

Across TCGA cell cohorts, SEL1L3 mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SEL1L3-associated genes across cancer lineages are GAGE12F, PYY, and OR10G2. Each is linked with SEL1L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEL1L3-to-partner and partner-to-SEL1L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12F grouped by SEL1L3-low versus SEL1L3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEL1L3→partner) and Y-score (partner→SEL1L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	GAGE12F →	+1.301	+4.635	<.001	.003	3	2
BLOOD_Leukemia	PYY →	+0.122	+3.612	.002	.004	3	2
BLOOD_Leukemia	OR10G2 →	+0.786	+2.966	<.001	.005	3	2
LARGE_INTESTINE	RAET1G →	+0.639	+3.451	.001	.002	3	2
PANCREAS	DEFB119 →	+0.231	+5.000	<.001	.006	3	1
BLOOD_Myeloma	KLRD1 →	+0.075	+3.321	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

GAGE12F by SEL1L3 expression — SOFT_TISSUE

Explore this box plot interactively →