SEL1L2

Across TCGA pan-cancer cohorts, SEL1L2 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SEL1L2 data layer compared with 24 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SEL1L2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SEL1L2 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC are the cancer types where SEL1L2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	II,III,IV	0.788	0.229	<.001	65	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

SEL1L2–PDAC (DFS)

Open the PDAC breakdown →