Across TCGA patient cohorts, SECISBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,853 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SECISBP2-associated genes across cancer lineages are GLE1, EXOSC2, and NAA35. Each is linked with SECISBP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SECISBP2-to-partner and partner-to-SECISBP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SECISBP2→partner) and Y-score (partner→SECISBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GLE1 →	+0.486	+0.182	<.001	.008	3	4
GBM	EXOSC2 →	+0.444	+0.261	<.001	<.001	3	4
BRCA	NAA35 →	+0.544	+0.299	<.001	.001	3	4
BRCA	RNF20 →	+0.399	+0.285	.004	.004	3	4
BRCA	EARS2 →	+0.443	+0.220	<.001	<.001	3	3
GBM	RAB14 →	+0.482	+0.230	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,853 associations by consensus.

Exploration

SECISBP2 survival (RNA) · tumor vs normal (RNA) · all SECISBP2 data types