Across TCGA patient cohorts, SECISBP2 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SECISBP2-associated genes across cancer lineages are Caspase-7-cleavedD198, ERK2, and P-Cadherin. Each is linked with SECISBP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SECISBP2-to-partner and partner-to-SECISBP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SECISBP2→partner) and Y-score (partner→SECISBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.676	+2.584	.001	.010	3	3
UCEC	ERK2 →	+0.183	+2.115	.008	.016	3	2
UCEC	P-Cadherin →	-0.151	-1.912	.003	.005	3	2
UCEC	Annexin-1 →	+0.601	+2.604	.001	.005	3	2
UCEC	Di-Ras3 →	-0.132	-2.584	.013	.010	3	2
UCEC	eEF2 →	+0.260	+1.584	.044	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

SECISBP2 survival (RNA) · tumor vs normal (RNA) · all SECISBP2 data types