Across TCGA cell cohorts, SECISBP2 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SECISBP2-associated genes across cancer lineages are LCL161, 123829, and GSK690693. Each is linked with SECISBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SECISBP2-to-partner and partner-to-SECISBP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SECISBP2→partner) and Y-score (partner→SECISBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCL161 →	+0.370	+2.646	.023	.047	3	1
LARGE_INTESTINE	123829 →	+0.575	+2.649	.049	.046	3	1
LARGE_INTESTINE	GSK690693 →	+0.626	+2.652	.012	.045	3	1
LARGE_INTESTINE	Nutlin-3a (-) →	+0.872	+2.646	.016	.047	1	1
LARGE_INTESTINE	IAP_5620 →	+0.417	+2.649	.023	.046	1	1
LARGE_INTESTINE	CZC24832 →	+0.297	+2.646	.021	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

SECISBP2 survival (RNA) · tumor vs normal (RNA) · all SECISBP2 data types