SEC24D

Across TCGA cell cohorts, SEC24D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,889 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SEC24D-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Regulation of protein exit from endoplasmic reticulum, and COPII-coated vesicle cargo loading. Each is linked with SEC24D in more than 19 cancer types. Because this analysis shows association rather than direction, both SEC24D-to-partner and partner-to-SEC24D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by SEC24D-low versus SEC24D-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC24D→partner) and Y-score (partner→SEC24D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of protein exit from endoplasmic reticulum →	+0.175	+1.356	<.001	<.001	3	20
LIVER	Regulation of protein exit from endoplasmic reticulum →	+0.182	+1.762	<.001	<.001	3	19
LIVER	COPII-coated vesicle cargo loading →	+0.192	+1.429	<.001	<.001	3	19
LIVER	Positive regulation of ER to Golgi vesicle-mediated transport →	+0.213	+1.482	<.001	<.001	3	17
BONE	Regulation of translation initiation in response to endoplasmic reticulum stress →	+0.141	+1.581	<.001	<.001	3	17
LIVER	Regulation of ER to Golgi vesicle-mediated transport →	+0.145	+1.436	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,889 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by SEC24D expression — OESOPHAGUS

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