SEC24C

Across TCGA cell cohorts, SEC24C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,233 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SEC24C-associated GO terms across cancer lineages are Cytosolic transport, COPI-coated vesicle budding, and Golgi transport vesicle coating. Each is linked with SEC24C in more than 15 cancer types. Because this analysis shows association rather than direction, both SEC24C-to-partner and partner-to-SEC24C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by SEC24C-low versus SEC24C-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC24C→partner) and Y-score (partner→SEC24C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.090	+1.129	<.001	<.001	3	16
STOMACH	COPI-coated vesicle budding →	+0.123	+0.709	<.001	<.001	3	16
STOMACH	Golgi transport vesicle coating →	+0.123	+0.709	<.001	<.001	3	16
STOMACH	COPI coating of Golgi vesicle →	+0.123	+0.709	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.068	+0.862	<.001	<.001	3	15
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.104	+1.031	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,233 associations by consensus.

Cytosolic transport by SEC24C expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →