SEC24B

Across TCGA cell cohorts, SEC24B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,108 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEC24B-associated GO terms across cancer lineages are Positive regulation of ER to Golgi vesicle-mediated transport, DNA alkylation repair, and Vesicle budding from membrane. Each is linked with SEC24B in more than 15 cancer types. Because this analysis shows association rather than direction, both SEC24B-to-partner and partner-to-SEC24B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of ER to Golgi vesicle-mediated transport grouped by SEC24B-low versus SEC24B-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC24B→partner) and Y-score (partner→SEC24B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of ER to Golgi vesicle-mediated transport →	+0.116	+0.624	.002	.004	3	16
PANCREAS	DNA alkylation repair →	+0.115	+0.736	<.001	<.001	3	15
LARGE_INTESTINE	Vesicle budding from membrane →	+0.078	+0.929	<.001	<.001	3	14
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.058	+0.632	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA catabolic process →	+0.052	+0.594	.001	.004	2	15
OVARY	Regulation of SREBP signaling pathway →	+0.126	+0.727	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,108 associations by consensus.

Positive regulation of ER to Golgi vesicle-mediated transport by SEC24B expression — KIDNEY

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