SEC23IP

Across TCGA cell cohorts, SEC23IP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,786 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SEC23IP-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Retrograde transport, endosome to Golgi, and Phosphatidylinositol biosynthetic process. Each is linked with SEC23IP in more than 15 cancer types. Because this analysis shows association rather than direction, both SEC23IP-to-partner and partner-to-SEC23IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by SEC23IP-low versus SEC23IP-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC23IP→partner) and Y-score (partner→SEC23IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Viral translational termination-reinitiation →	+0.102	+0.885	<.001	<.001	3	16
BONE	Retrograde transport, endosome to Golgi →	+0.089	+0.969	<.001	<.001	3	15
LARGE_INTESTINE	Phosphatidylinositol biosynthetic process →	+0.051	+0.982	<.001	<.001	3	14
LIVER	Spindle elongation →	+0.172	+0.790	<.001	.001	3	13
BONE	Endosomal transport →	+0.059	+0.759	.002	<.001	3	13
BONE	Regulation of hippo signaling →	+0.086	+0.735	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,786 associations by consensus.

Viral translational termination-reinitiation by SEC23IP expression — BLOOD_Lymphoma

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