SEC23A

Across TCGA cell cohorts, SEC23A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,030 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SEC23A-associated GO terms across cancer lineages are Vesicle cargo loading, COPII-coated vesicle cargo loading, and Spliceosome-depend formation of circular RNA. Each is linked with SEC23A in more than 14 cancer types. Because this analysis shows association rather than direction, both SEC23A-to-partner and partner-to-SEC23A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by SEC23A-low versus SEC23A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC23A→partner) and Y-score (partner→SEC23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Vesicle cargo loading →	+0.130	+1.227	<.001	<.001	3	15
BREAST	COPII-coated vesicle cargo loading →	+0.155	+1.150	<.001	<.001	3	14
LUNG_SCLC	Spliceosome-depend formation of circular RNA →	+0.219	+1.253	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.064	+1.299	.002	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hippo signaling →	+0.111	+1.134	<.001	.003	3	13
BONE	Regulation of cell-substrate junction assembly →	+0.136	+1.021	.002	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,030 associations by consensus.

Vesicle cargo loading by SEC23A expression — BONE

Explore this box plot interactively →