SEC22C

Across TCGA cell cohorts, SEC22C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,163 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEC22C-associated GO terms across cancer lineages are Microtubule polymerization, Regulation of mitotic sister chromatid separation, and Regulation of chromosome separation. Each is linked with SEC22C in more than 16 cancer types. Because this analysis shows association rather than direction, both SEC22C-to-partner and partner-to-SEC22C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by SEC22C-low versus SEC22C-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC22C→partner) and Y-score (partner→SEC22C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Microtubule polymerization →	+0.110	+0.756	.005	<.001	3	17
URINARY_TRACT	Regulation of mitotic sister chromatid separation →	+0.156	+1.007	.004	.001	3	15
URINARY_TRACT	Regulation of chromosome separation →	+0.116	+0.814	.008	.002	3	15
LARGE_INTESTINE	Microtubule polymerization or depolymerization →	+0.111	+0.896	<.001	<.001	3	15
URINARY_TRACT	Regulation of chromosome segregation →	+0.123	+1.024	.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Chromosome segregation →	+0.107	+1.039	.002	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,163 associations by consensus.

Microtubule polymerization by SEC22C expression — LIVER

Explore this box plot interactively →