SEC22A

Across TCGA cell cohorts, SEC22A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,651 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SEC22A-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Vesicle tethering to Golgi, and Positive regulation of protein localization to nucleolus. Each is linked with SEC22A in more than 10 cancer types. Because this analysis shows association rather than direction, both SEC22A-to-partner and partner-to-SEC22A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by SEC22A-low versus SEC22A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC22A→partner) and Y-score (partner→SEC22A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.093	+0.731	<.001	<.001	3	11
OESOPHAGUS	Vesicle tethering to Golgi →	+0.109	+0.733	.005	.002	3	10
OVARY	Positive regulation of protein localization to nucleolus →	+0.104	+0.549	<.001	.005	2	10
LIVER	Response to increased oxygen levels →	+0.175	+0.957	<.001	.002	3	9
SOFT_TISSUE	Enzyme-directed rRNA pseudouridine synthesis →	-0.113	-0.780	<.001	<.001	3	9
OVARY	Regulation of protein ubiquitination →	+0.067	+0.605	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,651 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by SEC22A expression — OVARY

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