Across TCGA pan-cancer cohorts, SEC14L6 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated SEC14L6 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher SEC14L6 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SEC14L6 expression acts as an unfavorable survival marker.

SARC are the cancer types where SEC14L6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SARC	OS	Median	All	0.085	0.839	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: SEC14L6 tumor-vs-normal RNA expression · all SEC14L6 data types