SEC14L4

Across TCGA patient cohorts, SEC14L4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,330 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SEC14L4-associated proteins across cancer lineages are PSME1, PSME2, and KIF2C. Each is linked with SEC14L4 in more than 2 cancer types. Because this analysis shows association rather than direction, both SEC14L4-to-partner and partner-to-SEC14L4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC14L4 versus PSME1 in COAD, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L4→partner) and Y-score (partner→SEC14L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PSME1 →	-0.379	-0.471	<.001	.001	3	3
COAD	PSME2 →	-0.443	-0.665	<.001	<.001	3	3
LUAD	KIF2C →	-0.507	-0.652	<.001	.001	3	3
GBM	ANXA4 →	+0.475	+0.342	<.001	.002	3	3
GBM	VWA5A →	+0.434	+0.325	<.001	.005	3	3
HNSC	NFKB1 →	-0.179	-0.502	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,330 associations by consensus.

SEC14L4 vs PSME1 — COAD

Explore this scatter interactively →