SEC14L4

Across TCGA patient cohorts, SEC14L4 protein abundance is significantly associated with the RNA expression of many other genes, with 3,755 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SEC14L4-associated genes across cancer lineages are HBA2, HBA1, and HBB. Each is linked with SEC14L4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SEC14L4-to-partner and partner-to-SEC14L4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC14L4 versus HBA2 in PDAC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L4→partner) and Y-score (partner→SEC14L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBA2 →	+2.546	+0.846	.004	.003	3	6
PDAC	HBA1 →	+1.849	+0.911	.002	<.001	3	6
PDAC	HBB →	+2.806	+0.941	.003	<.001	3	6
PDAC	PPBP →	+1.377	+0.677	<.001	.001	3	4
CCRCC	HEMGN →	+0.526	+0.747	<.001	<.001	3	4
PDAC	ALAS2 →	+1.104	+0.998	.005	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,755 associations by consensus.

SEC14L4 vs HBA2 — PDAC

Explore this scatter interactively →