SEC14L3

Across TCGA patient cohorts, SEC14L3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,109 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEC14L3-associated genes across cancer lineages are CHRDL1, MSLN, and BCAT2. Each is linked with SEC14L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEC14L3-to-partner and partner-to-SEC14L3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC14L3 versus CHRDL1 in OV, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L3→partner) and Y-score (partner→SEC14L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CHRDL1 →	+2.444	+2.280	.007	<.001	3	1
OV	MSLN →	+2.292	+1.717	.001	.001	3	1
OV	BCAT2 →	+0.948	+1.668	.002	.005	3	1
OV	PLEKHA8 →	-1.131	-1.904	.007	.001	3	1
OV	BCL7B →	-0.512	-1.548	.009	.005	3	1
OV	SLC35F2 →	+0.812	+1.697	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,109 associations by consensus.

SEC14L3 vs CHRDL1 — OV

Explore this scatter interactively →