SEC14L3

Across TCGA cell cohorts, SEC14L3 RNA expression is significantly associated with the go_rna of many other GO terms, with 471 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SEC14L3-associated GO terms across cancer lineages are Regulation of synaptic transmission, glutamatergic, Nucleic acid catabolic process, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with SEC14L3 in more than 5 cancer types. Because this analysis shows association rather than direction, both SEC14L3-to-partner and partner-to-SEC14L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synaptic transmission, glutamatergic grouped by SEC14L3-low versus SEC14L3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L3→partner) and Y-score (partner→SEC14L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of synaptic transmission, glutamatergic →	-0.082	-0.011	.001	.001	2	6
LARGE_INTESTINE	Nucleic acid catabolic process →	+0.031	+0.017	.002	.006	3	5
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.050	+0.017	.001	.007	3	5
LARGE_INTESTINE	RNA catabolic process →	+0.035	+0.013	.002	.002	3	5
LARGE_INTESTINE	mRNA catabolic process →	+0.030	+0.013	.009	.002	3	5
STOMACH	Negative regulation of DNA-templated transcription, elongation →	+0.108	+0.019	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 471 associations by consensus.

Regulation of synaptic transmission, glutamatergic by SEC14L3 expression — BLOOD_Lymphoma

Explore this box plot interactively →