SEC14L2

Across TCGA cell cohorts, SEC14L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,958 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SEC14L2-associated GO terms across cancer lineages are Barbed-end actin filament capping, Positive regulation of protein processing, and Wound healing. Each is linked with SEC14L2 in more than 13 cancer types. Because this analysis shows association rather than direction, both SEC14L2-to-partner and partner-to-SEC14L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Barbed-end actin filament capping grouped by SEC14L2-low versus SEC14L2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L2→partner) and Y-score (partner→SEC14L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Barbed-end actin filament capping →	+0.253	+1.786	<.001	<.001	3	14
BONE	Positive regulation of protein processing →	+0.186	+2.001	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Wound healing →	+0.139	+2.222	.003	<.001	3	13
LIVER	Caveola assembly →	+0.214	+1.844	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of extracellular matrix disassembly →	+0.158	+1.280	<.001	.001	3	12
LIVER	Positive regulation of extracellular matrix organization →	+0.147	+1.714	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,958 associations by consensus.

Barbed-end actin filament capping by SEC14L2 expression — BONE

Explore this box plot interactively →