Across TCGA pan-cancer cohorts, SEC13P1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of SEC13P1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where SEC13P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SEC13P1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.
COAD, BRCA, and BLCA are the cancer types where SEC13P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEC13P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.