SDSL

Across TCGA patient cohorts, SDSL RNA expression is significantly associated with the protein abundance of many other proteins, with 14,315 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SDSL-associated proteins across cancer lineages are RNF213, TPCN1, and KCTD15. Each is linked with SDSL in more than 4 cancer types. Because this analysis shows association rather than direction, both SDSL-to-partner and partner-to-SDSL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDSL versus RNF213 in LUAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SDSL→partner) and Y-score (partner→SDSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNF213 →	+0.433	+0.615	<.001	<.001	3	5
CCRCC	TPCN1 →	+0.316	+0.425	<.001	<.001	3	5
PDAC	KCTD15 →	-0.643	-0.409	.002	.001	3	5
LSCC	NHSL1 →	-0.454	-0.701	<.001	<.001	3	4
GBM	PARP4 →	+0.554	+0.553	<.001	<.001	3	4
LSCC	ARHGAP18 →	+0.400	+0.750	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,315 associations by consensus.

SDSL vs RNF213 — LUAD

Explore this scatter interactively →