Across TCGA cell cohorts, SDR42E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,138 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SDR42E1-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Regulation of ubiquitin-dependent protein catabolic process, and Small GTPase-mediated signal transduction. Each is linked with SDR42E1 in more than 10 cancer types. Because this analysis shows association rather than direction, both SDR42E1-to-partner and partner-to-SDR42E1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR42E1→partner) and Y-score (partner→SDR42E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.101	+1.654	<.001	<.001	3	11
URINARY_TRACT	Regulation of ubiquitin-dependent protein catabolic process →	+0.059	+1.957	.001	<.001	3	10
URINARY_TRACT	Small GTPase-mediated signal transduction →	+0.058	+1.893	<.001	<.001	3	10
BONE	Negative regulation of response to endoplasmic reticulum stress →	+0.142	+1.464	<.001	.002	3	10
BREAST	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	+0.186	+1.520	.008	.003	3	10
BONE	Regulation of intracellular protein transport →	+0.087	+1.408	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,138 associations by consensus.

Exploration

SDR42E1 survival (RNA) · tumor vs normal (RNA) · all SDR42E1 data types