SDR16C5

Across TCGA pan-cancer cohorts, SDR16C5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SDR16C5 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SDR16C5 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SDR16C5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where SDR16C5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	1.000	0.925	.002	41	view →
PDAC	OS	Quartile	II,III,IV	0.784	0.367	.004	12	view →
LUAD	OS	Median	All	0.889	0.999	.030	7	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

SDR16C5–HNSC (OS)

Open the HNSC breakdown →