SDK1

Across TCGA patient cohorts, SDK1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,171 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SDK1-associated genes across cancer lineages are SDK1-AS1, BATF2, and ANKRD22. Each is linked with SDK1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SDK1-to-partner and partner-to-SDK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDK1 versus SDK1-AS1 in LUAD, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDK1→partner) and Y-score (partner→SDK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SDK1-AS1 →	+1.077	+0.548	<.001	<.001	3	7
UCEC	BATF2 →	-1.064	-0.469	<.001	.007	3	4
UCEC	ANKRD22 →	-1.135	-0.553	.002	.002	3	3
HNSC	SOX2 →	+1.726	+0.362	<.001	.001	3	3
HNSC	NRXN3 →	+0.885	+0.514	.002	<.001	3	3
UCEC	BAK1 →	-0.890	-0.484	.004	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,171 associations by consensus.

SDK1 vs SDK1-AS1 — LUAD

Explore this scatter interactively →