SDHDP5

Across TCGA patient cohorts, SDHDP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,160 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SDHDP5-associated GO terms across cancer lineages are Regulation of DNA repair, Positive regulation of chromosome organization, and Negative regulation of mitotic cell cycle. Each is linked with SDHDP5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SDHDP5-to-partner and partner-to-SDHDP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by SDHDP5-low versus SDHDP5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHDP5→partner) and Y-score (partner→SDHDP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of DNA repair →	+0.068	+0.117	<.001	<.001	3	9
STAD	Positive regulation of chromosome organization →	+0.076	+0.119	<.001	<.001	3	8
STAD	Negative regulation of mitotic cell cycle →	+0.068	+0.123	<.001	<.001	3	8
STAD	Regulation of cell division →	+0.056	+0.107	<.001	<.001	3	8
STAD	Regulation of mitochondrial gene expression →	+0.067	+0.104	<.001	<.001	3	8
STAD	Negative regulation of intracellular protein transport →	+0.058	+0.105	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,160 associations by consensus.

Regulation of DNA repair by SDHDP5 expression — STAD

Explore this box plot interactively →