SDHDP1

Across TCGA patient cohorts, SDHDP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,990 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SDHDP1-associated GO terms across cancer lineages are Tetrapyrrole metabolic process, Purine nucleoside monophosphate biosynthetic process, and DNA-templated DNA replication maintenance of fidelity. Each is linked with SDHDP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SDHDP1-to-partner and partner-to-SDHDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tetrapyrrole metabolic process grouped by SDHDP1-low versus SDHDP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHDP1→partner) and Y-score (partner→SDHDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Tetrapyrrole metabolic process →	+0.031	+0.114	<.001	.004	3	10
UCEC	Purine nucleoside monophosphate biosynthetic process →	+0.039	+0.070	<.001	<.001	3	10
ESCA	DNA-templated DNA replication maintenance of fidelity →	+0.046	+0.118	<.001	<.001	3	9
STAD	Carbohydrate biosynthetic process →	+0.028	+0.123	<.001	.002	3	9
STAD	Protein targeting to mitochondrion →	+0.042	+0.161	<.001	<.001	3	9
STAD	Protein localization to mitochondrion →	+0.043	+0.142	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,990 associations by consensus.

Tetrapyrrole metabolic process by SDHDP1 expression — STAD

Explore this box plot interactively →