SDHCP3

Across TCGA pan-cancer cohorts, SDHCP3 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SDHCP3 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher SDHCP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SDHCP3 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

MESO, SKCM, and UVM are the cancer types where SDHCP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.272	0.647	.006	30	view →
SKCM	DFS	Median	II,III,IV	0.645	0.507	<.001	29	view →
UVM	OS	Tertile	III,IV	0.421	0.789	.004	28	view →
ACC	DFS	Quartile	II,III,IV	0.379	0.689	.014	19	view →
READ	OS	Median	IV	0.666	0.971	.011	12	view →
LUAD	DFS	Quartile	II,III,IV	0.488	0.148	.019	11	view →
ESCA	OS	Median	All	0.438	0.606	.020	9	view →
THCA	OS	Quartile	IV	0.589	0.899	.019	9	view →
CESC	OS	Median	All	0.494	0.665	.040	8	view →
TGCT	DFS	Median	All	0.499	0.745	.025	6	view →
KIRC	DFS	Median	III,IV	0.567	0.722	.008	5	view →
BLCA	OS	Tertile	IV	0.695	0.297	.019	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SDHCP3–MESO (OS)

Open the MESO breakdown →