Across TCGA patient cohorts, SDHAF3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,701 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SDHAF3-associated genes across cancer lineages are HTR7, SLC12A9-AS1, and FAM78A. Each is linked with SDHAF3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SDHAF3-to-partner and partner-to-SDHAF3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF3→partner) and Y-score (partner→SDHAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HTR7 →	-0.933	-0.356	<.001	<.001	3	4
UCEC	SLC12A9-AS1 →	+1.002	+0.489	<.001	<.001	3	4
HNSC	FAM78A →	-0.515	-0.311	.009	.007	3	3
HNSC	SEM1 →	+0.550	+0.438	<.001	<.001	3	3
HNSC	LRRCC1 →	+0.627	+0.364	.002	.007	3	3
HNSC	TMEM177 →	+0.742	+0.476	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,701 associations by consensus.

Exploration

SDHAF3 survival (RNA) · tumor vs normal (RNA) · all SDHAF3 data types