SDHAF2

Across TCGA patient cohorts, SDHAF2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,030 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SDHAF2-associated genes across cancer lineages are TRIP13, SDHA, and CCT5. Each is linked with SDHAF2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SDHAF2-to-partner and partner-to-SDHAF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDHAF2 versus TRIP13 in LUAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF2→partner) and Y-score (partner→SDHAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TRIP13 →	+1.273	+0.689	<.001	<.001	3	7
HNSC	SDHA →	+0.585	+0.577	<.001	<.001	3	7
HNSC	CCT5 →	+1.020	+0.681	<.001	<.001	3	6
OV	SEPTIN4 →	-0.563	-0.664	.004	.009	3	5
HNSC	FASTKD3 →	+0.570	+0.656	<.001	<.001	3	5
UCEC	NDUFS6 →	+0.976	+0.516	.006	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,030 associations by consensus.

SDHAF2 vs TRIP13 — LUAD

Explore this scatter interactively →