SDHAF2

Across TCGA cell cohorts, SDHAF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,190 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SDHAF2-associated GO terms across cancer lineages are Mitochondrial electron transport, succinate to ubiquinone, Regulation of attachment of mitotic spindle microtubules to kinetochore, and Anterograde axonal protein transport. Each is linked with SDHAF2 in more than 19 cancer types. Because this analysis shows association rather than direction, both SDHAF2-to-partner and partner-to-SDHAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, succinate to ubiquinone grouped by SDHAF2-low versus SDHAF2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF2→partner) and Y-score (partner→SDHAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial electron transport, succinate to ubiquinone →	+0.132	+0.678	<.001	<.001	3	20
LUNG_SCLC	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.119	+0.488	<.001	<.001	3	9
SOFT_TISSUE	Anterograde axonal protein transport →	-0.224	-0.460	<.001	<.001	3	9
OVARY	Maintenance of Golgi location →	+0.113	+0.704	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Response to staurosporine →	+0.146	+0.485	.001	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Cellular response to staurosporine →	+0.146	+0.485	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,190 associations by consensus.

Mitochondrial electron transport, succinate to ubiquinone by SDHAF2 expression — LUNG_SCLC

Explore this box plot interactively →