Across TCGA patient cohorts, SDHAF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,290 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SDHAF1-associated proteins across cancer lineages are UBA2, SAE1, and C9orf78. Each is linked with SDHAF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SDHAF1-to-partner and partner-to-SDHAF1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF1→partner) and Y-score (partner→SDHAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBA2 →	+0.302	+0.497	<.001	<.001	3	6
GBM	SAE1 →	+0.304	+0.354	<.001	<.001	3	6
COAD	C9orf78 →	+0.385	+0.562	.003	<.001	3	5
COAD	SIPA1L3 →	+0.418	+0.478	.005	.007	3	4
LSCC	STAG2 →	+0.280	+0.547	<.001	<.001	3	4
LSCC	THOC1 →	+0.220	+0.430	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,290 associations by consensus.

Exploration

SDHAF1 survival (RNA) · tumor vs normal (RNA) · all SDHAF1 data types