Across TCGA patient cohorts, SDHAF1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,888 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDHAF1-associated genes across cancer lineages are IDS, CFAP221, and DPP4. Each is linked with SDHAF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SDHAF1-to-partner and partner-to-SDHAF1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHAF1→partner) and Y-score (partner→SDHAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IDS →	-0.766	-0.587	<.001	.005	3	3
LUAD	CFAP221 →	-1.584	-0.942	<.001	<.001	3	3
LUAD	DPP4 →	-1.539	-0.676	<.001	<.001	3	3
UCEC	SLC1A2-AS1 →	-0.976	-0.504	<.001	<.001	3	3
UCEC	E2F1 →	+1.141	+0.535	<.001	<.001	3	2
LUAD	HLF →	-1.339	-0.805	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,888 associations by consensus.

Exploration

SDHAF1 survival (RNA) · tumor vs normal (RNA) · all SDHAF1 data types