SDHA

Across TCGA cell cohorts, SDHA protein abundance is significantly associated with the RNA expression of many other genes, with 3,838 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SDHA-associated genes across cancer lineages are FADS2, FAM71E1, and OSBPL10. Each is linked with SDHA in more than 2 cancer types. Because this analysis shows association rather than direction, both SDHA-to-partner and partner-to-SDHA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDHA versus FADS2 in BREAST, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDHA→partner) and Y-score (partner→SDHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	FADS2 →	-3.266	-1.186	.001	.003	3	3
STOMACH	FAM71E1 →	+1.215	+1.250	<.001	.002	3	2
STOMACH	OSBPL10 →	+1.905	+1.570	.003	.004	3	2
STOMACH	GPR107 →	+0.699	+1.169	.007	.005	3	2
STOMACH	MYO1C →	+1.539	+1.521	.001	.005	3	2
LUNG_NSCLC_LUAD	CZIB →	-0.510	-1.133	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,838 associations by consensus.

SDHA vs FADS2 — BREAST

Explore this scatter interactively →