SDF2L1

Across TCGA pan-cancer cohorts, SDF2L1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SDF2L1 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SDF2L1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SDF2L1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and COAD show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where SDF2L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.339	1.000	.003	26	view →
PDAC	DFS	Quartile	II,III,IV	0.962	0.690	.001	20	view →
GBM	DFS	Median	All	0.267	0.473	.004	11	view →
COAD	DFS	Median	IV	1.000	0.605	.043	6	view →
HNSC	DFS	Median	IV	1.000	0.413	.033	2	view →
LSCC	DFS	Tertile	All	0.852	0.450	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SDF2L1–CCRCC (OS)

Open the CCRCC breakdown →