SDF2

Across TCGA patient cohorts, SDF2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,111 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SDF2-associated genes across cancer lineages are DNAJB11, SENP2, and XXYLT1. Each is linked with SDF2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SDF2-to-partner and partner-to-SDF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDF2 versus DNAJB11 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDF2→partner) and Y-score (partner→SDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNAJB11 →	+0.655	+0.481	<.001	<.001	3	8
LSCC	SENP2 →	+0.663	+0.491	<.001	<.001	3	6
OV	XXYLT1 →	+0.756	+0.350	<.001	.002	3	6
UCEC	IGF2BP2 →	+1.922	+0.484	<.001	<.001	3	6
LSCC	PDCD10 →	+0.727	+0.448	<.001	<.001	3	6
LSCC	RAB6B →	+1.237	+0.327	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,111 associations by consensus.

SDF2 vs DNAJB11 — OV

Explore this scatter interactively →