SDF2

Across TCGA cell cohorts, SDF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,673 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SDF2-associated GO terms across cancer lineages are Endoplasmic reticulum to cytosol transport, Retrograde protein transport, ER to cytosol, and Protein exit from endoplasmic reticulum. Each is linked with SDF2 in more than 11 cancer types. Because this analysis shows association rather than direction, both SDF2-to-partner and partner-to-SDF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to cytosol transport grouped by SDF2-low versus SDF2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDF2→partner) and Y-score (partner→SDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Endoplasmic reticulum to cytosol transport →	+0.113	+0.444	<.001	<.001	3	12
BLOOD_Lymphoma	Retrograde protein transport, ER to cytosol →	+0.113	+0.444	<.001	<.001	3	12
BLOOD_Lymphoma	Protein exit from endoplasmic reticulum →	+0.108	+0.399	<.001	<.001	3	12
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.078	+0.739	<.001	<.001	3	11
BLOOD_Lymphoma	Protein catabolic process at synapse →	+0.149	+0.488	<.001	<.001	3	10
BLOOD_Lymphoma	Protein catabolic process at postsynapse →	+0.149	+0.488	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,673 associations by consensus.

Endoplasmic reticulum to cytosol transport by SDF2 expression — BLOOD_Lymphoma

Explore this box plot interactively →