SDC3

Across TCGA patient cohorts, SDC3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,942 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SDC3-associated genes across cancer lineages are P3H1, PI4K2A, and ERO1A. Each is linked with SDC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SDC3-to-partner and partner-to-SDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDC3 versus P3H1 in COAD, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDC3→partner) and Y-score (partner→SDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	P3H1 →	-0.919	-1.169	.009	.003	3	3
COAD	PI4K2A →	-0.634	-1.216	.007	.002	3	3
COAD	ERO1A →	-1.476	-0.887	.004	.006	3	3
GBM	CLN5 →	+0.475	+0.602	<.001	.001	3	2
OV	CRISPLD2 →	-1.321	-0.525	<.001	.004	3	2
GBM	AHR →	-0.919	-0.679	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,942 associations by consensus.

SDC3 vs P3H1 — COAD

Explore this scatter interactively →