SDC3

Across TCGA cell cohorts, SDC3 RNA expression is significantly associated with the RNA expression of many other genes, with 11,069 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SDC3-associated genes across cancer lineages are SELENON, SKI, and ZCCHC24. Each is linked with SDC3 in more than 12 cancer types. Because this analysis shows association rather than direction, both SDC3-to-partner and partner-to-SDC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDC3 versus SELENON in LARGE_INTESTINE, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDC3→partner) and Y-score (partner→SDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SELENON →	+1.602	+1.484	<.001	<.001	3	13
KIDNEY	SKI →	+1.347	+1.877	.001	.001	3	12
SKIN	ZCCHC24 →	+1.962	+2.339	<.001	<.001	3	11
BLOOD_Leukemia	PLBD2 →	+1.251	+1.188	<.001	<.001	2	12
LUNG_NSCLC_LUSC	CD99L2 →	+1.993	+1.952	<.001	<.001	3	10
OESOPHAGUS	MEGF8 →	+1.253	+1.434	.007	.002	1	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,069 associations by consensus.

SDC3 vs SELENON — LARGE_INTESTINE

Explore this scatter interactively →