SDC3

Across TCGA cell cohorts, SDC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,810 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SDC3-associated GO terms across cancer lineages are Cell division, Autophagy, and Neuron migration. Each is linked with SDC3 in more than 11 cancer types. Because this analysis shows association rather than direction, both SDC3-to-partner and partner-to-SDC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by SDC3-low versus SDC3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDC3→partner) and Y-score (partner→SDC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cell division →	+0.058	+1.570	<.001	<.001	3	12
OESOPHAGUS	Autophagy →	+0.081	+1.221	<.001	.003	3	11
LUNG_SCLC	Neuron migration →	+0.108	+1.818	.001	.001	3	11
LUNG_NSCLC_LUAD	COPI-coated vesicle budding →	+0.060	+0.872	.005	.004	2	12
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.081	+1.221	<.001	.003	3	11
LUNG_NSCLC_LUAD	Golgi transport vesicle coating →	+0.060	+0.872	.005	.004	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,810 associations by consensus.

Cell division by SDC3 expression — LUNG_SCLC

Explore this box plot interactively →