SDC2

Across TCGA cell cohorts, SDC2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SDC2-associated genes across cancer lineages are OPN4 and ODF1. Each is linked with SDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDC2-to-partner and partner-to-SDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN4 grouped by SDC2-low versus SDC2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDC2→partner) and Y-score (partner→SDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OPN4 →	+0.013	+4.930	.007	.001	3	1
SKIN	ODF1 →	+0.020	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OPN4 by SDC2 expression — LARGE_INTESTINE

Explore this box plot interactively →