SDC1

Across TCGA cell cohorts, SDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,410 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SDC1-associated GO terms across cancer lineages are Myoblast development, Positive regulation of extracellular exosome assembly, and Positive regulation of protein localization to cell periphery. Each is linked with SDC1 in more than 18 cancer types. Because this analysis shows association rather than direction, both SDC1-to-partner and partner-to-SDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myoblast development grouped by SDC1-low versus SDC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDC1→partner) and Y-score (partner→SDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Myoblast development →	+1.718	+3.879	<.001	<.001	3	19
LUNG_SCLC	Positive regulation of extracellular exosome assembly →	+0.251	+1.508	<.001	<.001	3	15
STOMACH	Positive regulation of protein localization to cell periphery →	+0.118	+1.943	.001	.004	3	10
LUNG_NSCLC_LUAD	Cell junction assembly →	+0.075	+1.392	<.001	<.001	3	10
LUNG_SCLC	Regulation of extracellular exosome assembly →	+0.186	+1.419	<.001	<.001	3	10
BONE	Cell-cell junction organization →	+0.098	+4.264	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,410 associations by consensus.

Myoblast development by SDC1 expression — BONE

Explore this box plot interactively →