Across TCGA pan-cancer cohorts, SDAD1P4 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SDAD1P4’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SDAD1P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SDAD1P4 is over-expressed in tumor.
LUSC are the cancer types where SDAD1P4 tumor–normal differential expression is most reproducible.