Across TCGA cell cohorts, SDAD1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SDAD1-associated genes across cancer lineages are OPN4, ACP7, and ETDB. Each is linked with SDAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDAD1-to-partner and partner-to-SDAD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDAD1→partner) and Y-score (partner→SDAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OPN4 →	+0.043	+3.536	<.001	.001	3	1
BLOOD_Leukemia	ACP7 →	+0.026	+3.345	<.001	.009	3	1
BLOOD_Leukemia	ETDB →	+0.039	+3.381	.001	.002	3	1
BLOOD_Leukemia	LBHD2 →	+0.025	+4.247	<.001	.004	3	1
BLOOD_Leukemia	CNTNAP3C →	+0.078	+4.051	.003	.002	3	1
BLOOD_Lymphoma	NPPB →	+0.066	+3.421	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

SDAD1 survival (RNA) · tumor vs normal (RNA) · all SDAD1 data types