SDAD1-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SDAD1-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SDAD1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where SDAD1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SDAD1-AS1 is over-expressed in tumor, although a few such as THCA and KIRP show the opposite, repressed pattern.

BRCA, HNSC, and KIRC are the cancer types where SDAD1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SDAD1-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllAll+0.096.0036view →
HNSCAllII,III,IV+0.023.0135view →
KIRCMaleAll+0.022.0085view →
THCAFemaleII,III,IV−0.042.0034view →
KIRPMaleAll−0.023.0174view →
CHOLAllAll+0.072.0042view →
STADMaleAll+0.047.0332view →
COADAllAll+0.036.0112view →
LUSCAllAll+0.028.0302view →
LUADAllAll+0.113.0381view →
LIHCFemaleAll+0.012.0481view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SDAD1-AS1–BRCA

Tumor-vs-normal expression box plot for SDAD1-AS1 RNA in BRCA.

Open the BRCA breakdown →

Exploration