SCYL3

Across TCGA cell cohorts, SCYL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,255 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SCYL3-associated GO terms across cancer lineages are Glycerolipid biosynthetic process, Copper ion export, and Cilium-dependent cell motility. Each is linked with SCYL3 in more than 14 cancer types. Because this analysis shows association rather than direction, both SCYL3-to-partner and partner-to-SCYL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycerolipid biosynthetic process grouped by SCYL3-low versus SCYL3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYL3→partner) and Y-score (partner→SCYL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Glycerolipid biosynthetic process →	+0.048	+0.551	<.001	<.001	3	15
LARGE_INTESTINE	Copper ion export →	-0.162	-0.755	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.123	-0.846	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.123	-0.846	<.001	<.001	3	14
STOMACH	mRNA 3'-end processing →	+0.077	+0.670	.008	.002	3	13
LUNG_SCLC	Regulation of alternative mRNA splicing, via spliceosome →	+0.088	+0.575	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,255 associations by consensus.

Glycerolipid biosynthetic process by SCYL3 expression — STOMACH

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